Skip to main content

Posts

Showing posts from September, 2023

Cleaning validation Part 2 [ General Cleaning Methods and Concepts]

  General Cleaning Methods and Concepts Cleaning methods are broadly divided in to three types (1) manual cleaning method (2) Semi-automated  cleaning procedure & (3) fully automated system. whatever the cleaning method used for cleaning, it is necessary that each cleaning procedure should be fully documented and controlled. The standard operating procedure shall be available for each type of cleaning methods. The documentation should include a clear and unambiguous definition of its intended scope and applicability. This includes definition of a processing equipment and products to which it is applies. For example a clear distinction must be made between an abbreviated cleaning procedure designed for use between batches of the same product and a rigorous cleaning procedure designed for use between batches of different products. In some cases it is best to dedicate the use of some equipment's to certain products. For example filter bags used in FBD. By dedicating the some ...